Pentostatin (or deoxycoformycin, trade name Nipent, manufactured by SuperGen) is an anticancer chemotherapeutic drug. Mechanism. It is classified as a purine analog, which is a type of antimetabolite. It mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, interfering with the cell's ability to process DNA.

Please note the following when using Package Inserts from this web site: The drug labels and other drug-specific information on this website represent the most recent drug listing information that companies have provided to, or which is obtainable by, the Division of AIDS, NIAID, NIH (“DAIDS”), and are made available here in support of DAIDS-funded and/or -sponsored clinical trials, both

2 oxaliplatin Apr 18, 2014 For multi-drug regimens, select antiemetic therapy based on the drug with the highest emetic risk. See Emetogenic Pentostatin. • Pralatrexate chemotherapy on day 1 only, per the package insert.97 If a higher dose. Stability news, new stability studies, new monographs, summaries of international congresses etc. Simply insert your email address on the www.stabilis.org NIPENT was used to treat patients with confirmed IFN-refractory disease. In the SWOG 8691 study, NIPENT was administered at a dose of 4 mg/m2 every 2 weeks.

Nipent package insert

If a complete response was achieved, 2 additional doses of NIPENT were administered and then discontinued. NIPENT ™ (pentostatin for injection) is supplied as a sterile, apyrogenic, lyophilized powder in single-dose vials for intravenous administration. Each vial contains 10 mg of pentostatin and 50 mg of Mannitol, USP. NIPENT™ (pentostatin) This product information is intended only for residents of the United States. Nipent (pentostatin for injection) is supplied as a sterile lyophilized white to off-white powder in single-dose vials containing 10 mg of pentostatin. The vials are packed in individual cartons. NDC 0409-0801-09. Storage.

NIPENT was used to treat patients with confirmed IFN-refractory disease. In the SWOG 8691 study, NIPENT was administered at a dose of 4 mg/m2 every 2 weeks. After 6 months of treatment, patients were evaluated for response. If a complete response was achieved, 2 additional doses of NIPENT were administered and then discontinued.

Recently, it has been shown that the anti-leukemia drug pentostatin (Figure 2), i.e., the Mutamycin, Mylotarg, Navelbine, Nipent, Novantrone, Oncaspar, Ontak, The package insert for any and all products used in the preparation of TPN products. demethylating chemotherapy drug. drugs that inhibit the enzyme methyltransferase, which normally transfers a methyl group and inserts it into DNA during cell Drug product requiring repackaging, compounding, or manipulation: Double pair of chemotherapy gloves and chemotherapy gown. Vaginal Insert.

Generic/alternate drug name. C9014 DEXAMETHASONE, LACRIMAL OPHTHALMIC INSERT, 0.1 MG. C9049 PENTOSTATIN INJECTION. J9270.

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See full prescribing information for HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use REVLIMID® safely and effectively. See full prescribing information for NIPENT vials are stable at refrigerated storage temperature 2° to 8° C (36° to 46°F) for the period stated on the package. Vials reconstituted or reconstituted and further diluted as directed may be stored at room temperature and ambient light but should be used within 8 hours because NIPENT … Nipent (pentostatin) Non-Oncology Policy (Intravenous) Department: PHA Effective Date: 09/01/2020 Review Date: 8/3/2020 Revision Date: Purpose: To support safe, effective and appropriate use of Nipent (pentostatin). Scope: Medicaid, Commerical, Medicare-Medicaid Plan (MMP) Policy Statement: P03951_16/SK00621-5 p. 3/38 . Merck Sharp & Dohme sponsored clinical study, KEYNOTE-024 (KN024), investigated the clinical validity of PDL1 IHC 22C3 pharmDx - Nipent ® (pentostatin) is a prescription medication approved to treat hairy cell leukemia in adults. Hairy cell leukemia is an uncommon type of cancer that affects a certain type of white blood cell known as B-cells.
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Hairy cell leukemia is an uncommon type of cancer that affects a certain type of white blood cell known as B-cells.

Type the title in sentence-case, capitalizing only the first word and any proper nouns. Place a period at the end of the title. COMMON BRAND NAME(S): Nipent .
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Respiratory Protection**. Administering/wasting from unit-dose package Nipent . Perjeta, Phesgo. N/A. Polivy. Pemazyre. Folotyn. Matulane. All trade names.

Drug Facts and Comparisons. Drug Facts and Comparisons 4.0 [online]. 2012. NIPENT vials are stable at refrigerated storage temperature 2° to 8° C (36° to 46°F) for the period stated on the package.

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ACCORDANCE WITH THIS PACKAGE INSERT. NO OTHER RIGHTS ARE CONVEYED EXPRESSLY, BY IMPLICATION OR BY ESTOPPEL. FURTHERMORE, NO RIGHTS FOR RESALE ARE CONFERRED WITH THE PURCHASE OF THIS PRODUCT. Copyright © 2019 Cepheid. All rights reserved. Cepheid 904 Caribbean Drive Sunnyvale, CA 94089-1189 USA For Information Only - Not A Controlled Copy

Sep 14, 2020 Policy Number: RxA.170.